Речь идет о генетически измененных макрофагах — клетках иммунной системы, которые в норме могут пересекать гематоэнцефалический барьер. Исследователи снабдили их химерным антигенным рецептором (CAR), нацеленным на белок мезотелин, характерный для ряда опухолей, включая рак легких, молочной железы и меланому. Дополнительно в конструкцию встроили сигнальную молекулу MyD88, усиливающую противоопухолевую активность клеток. Полученные клетки назвали CARMA.
Scaling up performance from M5 and offering the same breakthrough GPU architecture with a Neural Accelerator in each core, M5 Pro and M5 Max deliver up to 4x faster LLM prompt processing than M4 Pro and M4 Max, and up to 8x AI image generation than M1 Pro and M1 Max.2 This enables AI researchers and developers to train custom models locally, and creative professionals to leverage AI-powered tools for video editing, music production, and design work. Both chips also bring up to a 50 percent increase in graphics performance compared to M4 Pro and M4 Max,3,4 enabling motion designers to work with complex 3D scenes in real time and VFX artists to preview effects instantly. And with a faster and more power-efficient Neural Engine and higher unified memory bandwidth, the new MacBook Pro delivers incredible on-device AI capabilities. The increase in unified memory bandwidth enables complex workflows like intensive AI model training and massive video projects. M5 Pro supports up to 64GB of unified memory with up to 307GB/s of memory bandwidth, while M5 Max supports up to 128GB of unified memory with up to 614GB/s of memory bandwidth.
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