Author Correction: Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21

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"The first time there's any type of struggle, the immediate thought is, 'well, I thought you were my soulmate. But maybe you're not, because soulmates aren't supposed to deal with things'," he says. "But if relationships are going to go long term, it's never just going to be a downhill run."

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And there are some exquisite, multicoloured glass beads. Measuring about 3mm across, each one is a miniature delight. They were possibly stitched onto clothing or attached to a piece of jewellery.